Craniofacial Embryogenetics and Development (2nd Edition)
Geoffrey H. Sperber, Steven M. Sperber, Geoffrey D. Guttmann, Phillip V. Tobias
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Recent advances in genetics, molecular biology, diagnostic imaging and surgical techniques require a substantial understanding of prenatal development morphogenesis. The clinical significance of the normal mechanisms of embryogenesis, developmental failures and consequent craniofacial anomalies is of increasing concern to plastic and orofacial surgeons, otolaryngologists, orthodontists, neonatologists, and speech pathologists. This second edition will …….
Clinicians dealing with malformations needing comprehension of the exponential expansion of information on molecular genomics, dysgenesis, teratology and the etiology of syndromes and anomalies are served by this book’s succinct contents. While providing clinicians with a basic background for treating craniofacial anomalies, this text will also appeal to teratologists, embryologists, and anatomists.
The glands derived from the endodermal lining of the pouch lose their connection with the pharyngeal wall when the pouches become obliterated during later development. The lateral glossoepiglottic fold represents the third pharyngeal pouch. Fourth Pharyngeal Pouch The fate of the endoderm of the ventral diverticulum is uncertain: the lining membrane may contribute to thymus or thyroid tissue. The dorsal diverticulum endoderm differentiates into the superior parathyroid gland (parathyroid IV), which, after losing contact with the pharynx, migrates caudally with the thyroid gland.
Other defects of facial development have been dealt with on p. 55. SELECTED BIBLIOGRAPHY Arnold WH, Sperber GH, Machin GA. Cranio-facial skeletal development in three human synophthalmic holoprosencephalic fetuses. Anat Anz 1998; 180: 45–53. Sperber_09_F. indd Sec1:129 12/2/09 5:57:03 PM 130 Craniofacial Development Cussenot O, Zouaoui A, Hidden G. Growth of the facial bones of the fetus. Surg Radiol Anat 1990; 12:230–231. Flugel C, Schram K, Rohen JW. Postnatal development of skull base, neuro- and viscerocranium in man and monkey: morphometric evaluation of CT scans and radiograms.
In Advances in anatomy, embryology and cell biology. New York: Springer Verlag, 1985:98; by permission; see Figure 3–4. ) septum—and paired lateral masses, the ectethmoid, that will form the paired ethmoidal (conchal) and nasal alar cartilages (Fig. 3–15). A cartilaginous nasal floor does not develop in the human. Initially, the primitive nasal septum is a broad area between the primary choanae, and never projects as a free process, but builds up in a rostrocaudal direction as the laterdeveloping palatal shelves fuse.
Ncbi. nlm. nih. gov/genome/guide/human/ www. med. unc. edu/embryo_images/ http://virtualhumanembryo. lsuhsc. edu/ Sperber_01_F. indd 11 12/2/09 4:22:05 PM Sperber_01_F. indd 12 12/2/09 4:22:05 PM 2 Early Embryonic Development Over the structure of the cell rises the structure of plants and animals, which exhibit the yet more complicated, elaborate combinations of millions and billions of cells coordinated and differentiated in the most extremely different way. Oscar Hertwig The mating of male and female gametes in the maternal uterine tube initiates the development of a zygote—the first identification of an individual.
Larsen’s human embryology. 4th ed. New York,. Churchill Livingstone, 2009. Shuler CF. Programmed cell death and cell transformation in craniofacial development. Crit Rev Oral Biol Med 1995; 6:202–217. Smith CM, Finger JH, Hayamizu TF, et al. The Gene Expression Database (GXD): A resource for developmental biologists. Dev Biol 2008; 319:564. Sperber GH. First year of life: prenatal craniofacial development. Cleft PalateCraniofac J 1992; 29:109–111. Sperber GH. Current concepts in embryonic craniofacial development.